Role of closed loop IntelliVent ventilation mode in head injury patients requiring mechanical ventilation

Comparative analysis of closed loop IntelliVent mode ventilation in head injury patients to conventional SIMV ventilation modes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10127188

Enrollment

100

Registered

2020-06-23

Start date

2018-11-01

Completion date

Unknown

Last updated

2020-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head injury Injury, Occupational Diseases, Poisoning

Interventions

Patients with head injury fulfilling the inclusion criteria were selected and randomly allocated into two groups. Informed consent was taken from all the patients falling in inclusion criteria. Rando

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Head injury with rapidly deteriorating GCS within 24 hrs 2. Patients with GCS less than 8/15 requiring mechanical ventilation

Exclusion criteria

Exclusion criteria: 1. GCS of 3/15 with head injury 2. Blunt trauma to the chest 3. Lung pathologies 4. Extremes of ages, infants, neonates and elderly 5. Co-morbidities such as DM, HTN

Design outcomes

Primary

Measure	Time frame
End tidal CO2 was measured as a primary outcome of effective ventilation. The ETCO2 was measured at 6 hrs interval and then averaged over 48 hrs and filled on the questionnaire. ETCO2 for first 48 hrs was taken as a measure of ventilation.	—

Secondary

Measure	Time frame
Prevention of secondary insult during stay assessed with variables as the length of ICU stay, ICU mortality and hospital mortality using patient records	—

Countries

Pakistan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026