Skip to content

Can we predict the risk of cancer or precancer in postmenopausal women with polyps in their womb?

Risk of premalignancy or malignancy in postmenopausal endometrial polyps: a CHAID decision tree analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN10094287
Enrollment
200
Registered
2020-06-24
Start date
2015-10-07
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial polyps Urological and Genital Diseases Polyp of corpus uteri

Interventions

This was an observational study only. Consecutive postmenopausal women referred by their general practitioners to the outpatient gynaecology unit were potentially eligible. All women had a routine tra

Sponsors

University College London Hospitals NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Postmenopausal 2. Aged 45 years or above 3. At least 1 year history of amenorrhea 4. Diagnosed with endometrial polyps on transvaginal ultrasound and underwent hysteroscopic polypectomy or hysterectomy within 2 months of the diagnosis

Exclusion criteria

Exclusion criteria: 1. Hysterectomy 2. Known endometrial hyperplasia or cancer 3. Use of tamoxifen

Design outcomes

Primary

MeasureTime frame
Presence or absence of premalignancy or malignancy in endometrial polyps diagnosed using transvaginal ultrasound at baseline scan

Secondary

MeasureTime frame
Risk factors for premalignancy or malignancy in endometrial polyps were taken from the patient's medical records at the time of their clinical assessment. Patient characteristics and ultrasound morphological features were then analysed after the researchers had obtained histological diagnoses of the polyps in order to identify predictive risk factors.

Countries

England, United Kingdom

Contacts

Public ContactMichael Wong
michael.wong3@nhs.net+44 (0)20 3447 9411

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026