Digitally enhanced targeted testing for HIV, hepatitis B and hepatitis C in primary care (TARGET-ID): feasibility study

Undiagnosed HIV, Hepatitis B and Hepatitis C in primary care: Targeted testing using digital technology to increase identification and improve care pathways for higher risk and underserved communities (TARGET-ID): Randomised mixed methods feasibility study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN10073032

Enrollment

1200

Registered

2024-10-08

Start date

2025-04-01

Completion date

Unknown

Last updated

2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Identification of patients at risk of HIV, Hepatitis B and Hepatitis C. Infections and Infestations

Interventions

• A computer search will identify 200 patients per practice who are most at risk of the blood-borne viruses (BBV) HIV, hepatitis B and hepatitis C. • A text message including links to an explanatory

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individuals aged 18 and above registered with one of the participating general practices, who can undertake the pre-test discussion in English or with a suitable translator.

Exclusion criteria

Exclusion criteria: 1. Age under 18 years 2. Known BBV positive patients 3. Individuals with limited English abilities, who are unable to understand the info sheet or, who are unable to engage with the pre-test discussion for BBV testing

Design outcomes

Primary

Measure	Time frame
Numbers of patients newly diagnosed with HIV, HBV or HCV measured using patient records at follow up	—

Secondary

Measure	Time frame
Measured using patient records at follow up: Clinical outcomes 1. Numbers of patients diagnosed at an early stage of HIV (CD4 count at or above 350 cells per cubic millimetre of blood) 2. Numbers of patients diagnosed with Hepatitis B with liver cirrhosis 3. Numbers of patients diagnosed with Hepatitis C with liver cirrhosis Viral outcomes 4. Initial viral load for HIV, HBV and HCV Health service use 5. Numbers of patients identified at different levels of risk for each BBV 6. Numbers offered testing 7. Numbers accepted testing and had a test 8. Numbers accepted testing but did not attend following three invitations 9. Numbers declined testing 10. Numbers of non-responders 11. Positive tests and yield 12. Numbers referred to peer supporters 13. Numbers referred to specialist clinics 14. Numbers of patients who entered the clinic Economic outcomes 15. Cost-effectiveness of the intervention compared to standard of care 16. Practice activities measured using observation of clinical meetings, data from practice GP or nurse champion	—

Measure

Time frame

Measured using patient records at follow up: Clinical outcomes 1. Numbers of patients diagnosed at an early stage of HIV (CD4 count at or above 350 cells per cubic millimetre of blood) 2. Numbers of patients diagnosed with Hepatitis B with liver cirrhosis 3. Numbers of patients diagnosed with Hepatitis C with liver cirrhosis Viral outcomes 4. Initial viral load for HIV, HBV and HCV Health service use 5. Numbers of patients identified at different levels of risk for each BBV 6. Numbers offered testing 7. Numbers accepted testing and had a test 8. Numbers accepted testing but did not attend following three invitations 9. Numbers declined testing 10. Numbers of non-responders 11. Positive tests and yield 12. Numbers referred to peer supporters 13. Numbers referred to specialist clinics 14. Numbers of patients who entered the clinic Economic outcomes 15. Cost-effectiveness of the intervention compared to standard of care 16. Practice activities measured using observation of clinical meetings, data from practice GP or nurse champion

—

Countries

England, United Kingdom

Contacts

Public ContactWerner Leber

w.leber@qmul.ac.uk+44 20 7882 7084

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026