Second trimester termination of pregnancy, outcome after one or two day mifepristone-misoprostol interval

Second trimester termination of pregnancy, outcome after one or two day mifepristone-misoprostol interval: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN09944151

Enrollment

200

Registered

2009-01-16

Start date

2008-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Termination of second trimester pregnancy Pregnancy and Childbirth Unspecified abortion

Interventions

The study is a prospective, randomised, single-centre study of about 150 patients seeking a second trimester termination of pregnancy at Helsinki University Hospital during 01/06/2008-31/06/2009. Th

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Age over 18 years 2. Duration of pregnancy (as verified by ultrasonography) between 12 weeks (12+1) up to 24 weeks (24+0) and approval for termination from the Finnish National Authority for Medico-legal Affairs (TEO) 3. Singleton, live pregnancy 4. Voluntary participation and signed approval to the study 5. No intrauterine device (IUD) in utero at the time of abortion

Exclusion criteria

Exclusion criteria: 1. Allergy to mifepristone or misoprostol 2. Severe, complicated asthma 3. An extrauterine pregnancy 4. No common language with the investigators 5. A coronary disease or high risk factors for it 6. HIV or hepatitis (a smaller group having blood samples taken)

Design outcomes

Primary

Measure	Time frame
1. Time to termination of pregnancy 2. Need for surgical curettage	—

Secondary

Measure	Time frame
No secondary outcome measures	—

Countries

Finland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 28, 2026