Blood Stream Infections Infections and Infestations Bacteraemia
Conditions
Interventions
The study will be of a prospective cohort design and will involve the collection of data from each of the five centres Newcastle, Leeds, Cardiff, London and Bristol, to generate a large clinical libra
Sponsors
North Bristol NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18 years of age and over 2. Blood Stream Infection with one of the key pathogens plus Centres of Disease Control criteria for infection in the urinary tract, surgical site, pneumonia, blood stream, bone and joint, central nervous system, cardiovascular system, ENT, gastrointestinal system, reproductive system, skin and skin structure, infection or disseminated infection. 3. Blood Stream Infection with any other organism for collection of the limited data set
Exclusion criteria
Exclusion criteria: 1. Less than 18 years of age 2. Having cystic fibrosis 3. Having disease associated with human immunodeficiency virus 4. Patients on the end of care pathway 5. Duplicate organism (same organism within 14 days of previous blood culture) 6. Prisoners or young offenders in the custody of HM Prison Service in England or Wales
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality and time to death (up to 28 days from when the blood samples was taken) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Resolution of fever (temperature =48 hours) and time to resolution of fever (up to 28 days from when the blood samples was taken) 2. Discharge from hospital and time to discharge (up to 28 days from when the blood samples was taken) 3. C. difficile infection (up to 28 days from when the blood samples was taken) | — |
Countries
United Kingdom
Outcome results
None listed