Topic: Neurological disorders
Conditions
Interventions
Participants will be individually randomised (6:5) to allow for clustering in intervention arm to intervention or control, stratified by recruitment site and minimised by MS-type (relapsing-remitting
Sponsors
University of Nottingham (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Are 18 or over and under 70 years of age. The lower age limit is because MS is usually diagnosed in adulthood and treatment strategies tend to be different for children. People aged 70 and over may start to encounter age-related cognitive problems, which may confound the effects of cognitive problem due to MS. Also, most tests are standardised on this adult age group. 2. Have relapsing or progressive MS, diagnosed at least 3 months prior to the baseline assessment contact with the study team, to allow for adjustment to diagnosis. Report having cognitive problems as determined by a cut-off score of >27 on the patient version of the Multiple Sclerosis Neuropsychological Screening Questionnaire (MSNQ). This cut-off is based on previous research and is two standard deviations below the mean for healthy participants. 3. Have cognitive deficits, defined as performance below the 25th percentile on the Brief Repeatable Battery of Neuropsychological Tests (BRBN). 4. Are able to travel to one of the centres and attend group sessions. 5. Are able to speak English sufficiently to complete the cognitive assessments and take part in group sessions. 6. Give informed consent.
Exclusion criteria
Exclusion criteria: 1. Vision or hearing problems, such that they are unable to complete the cognitive assessments, judged by assessor. 2. Have concurrent severe medical or psychiatric conditions which would prevent participants from engaging in treatment, if allocated. 3. Are involved in other psychological intervention trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psychological impact of MS; Timepoint(s): 12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Memory problems in everyday life; Timepoint(s): 6 and 12 months 2. Mood; Timepoint(s): 6 and 12 months 3. Fatigue; Timepoint(s): 6 and 12 months 4. Carer strain; Timepoint(s): 6 and 12 months 5. Quality of Life; Timepoint(s): 6 and 12 months 6. Attention and memory abilities; Timepoint(s): 6 and 12 months 7. Physical impact of MS; Timepoint(s): 6 and 12 months 8. Cost-effectiveness; Timepoint(s): 6 and 12 months 9. Employment status; Timepoint(s): 6 and 12 months 10. Number of reported relapses in the previous six months; Timepoint(s): 6 and 12 months 11. Disability; Timepoint(s): 6 and 12 months | — |
Countries
United Kingdom
Outcome results
None listed