The Diabetes Risk Communication Trial (DRCT)

Effect of communicating genetic and phenotypic risk for type 2 diabetes in combination with lifestyle advice on objectively measured physical activity: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN09650496

Enrollment

580

Registered

2011-06-10

Start date

2011-02-11

Completion date

Unknown

Last updated

2016-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes/physical activity/risk communication Nutritional, Metabolic, Endocrine Type 2 diabetes mellitus

Interventions

Participants are randomly allocated to one of three groups: Intervention Group A: Participants receive a genetic risk estimate for type 2 diabetes based on 23 single nucleotide polymorphisms Inte

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Residents of Cambridgeshire, in the east of England, born between 1950 and 1975, are potentially eligible to participate in the Fenland Study. Participants of the Fenland Study are invited to take part in the DRCT if they: 1. Agreed to be contacted regarding potential involvement in future studies 2. Provided sufficient data to calculate genetic and phenotypic risk estimates for type 2 diabetes 3. Wore an Actiheart® for 3 or more full days without experiencing a severe rash 4. Returned an Actiheart® that recorded 36 or more hours of total data

Exclusion criteria

Exclusion criteria: Residents of Cambridgeshire are excluded from the Fenland Study by their GP if they: 1. Have diagnosed diabetes 2. Have a medical condition with a prognosis of less than 1 year 3. Suffer from psychotic illness 4. Are pregnant or lactating 5. Are unable to walk unaided After participating in the Fenland Study, participants are excluded from the DRCT if they: 1. Have diagnosed diabetes 2. Are actively participating in another study

Design outcomes

Primary

Measure	Time frame
Objectively measured physical activity energy expenditure over 1 week (8 weeks post-intervention), assessed using an Actiheart®	—

Secondary

Measure	Time frame
1. Self-reported diet 2. Self-reported weight 3. Intentions to be physically active and to engage in a healthy diet 4. Anxiety 5. Diabetes-related worry 6. Self-rated health 7. Self-reported sedentary behaviour 8. Cognitive and emotional theory-based antecedents to health behaviour change	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 28, 2026