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Evaluation of cardiac biomarker elevation after percutaneous coronary intervention or coronary artery bypass graft

Prognostic evaluation of cardiac biomarker elevation after percutaneous and surgical revascularization in the absence of manifested myocardial infarction: a comparative analysis of biomarkers and cardiac magnetic resonance

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN09454308
Enrollment
150
Registered
2012-05-08
Start date
2012-04-25
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with multivessel coronary artery disease and stable angina with formal indication for revascularization procedures Circulatory System Angina pectoris, unspecified

Interventions

Percutaneous coronary intervention using stents - 5 year follow-up Coronary artery bypass graft with cardiopulmonary bypass (on-pump) - 5 year follow-up Coronary artery bypass graft without cardiopulm

Sponsors

Zerbini Foundation [Fundação Zerbini] (Brazil)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Stable angina 2. Multi-vessel coronary artery disease 3. Preserved left ventricular function 4. Formal indication to revascularization procedures (PCI or CABG)

Exclusion criteria

Exclusion criteria: 1. Recent myocardial infarction (=6 months) 2. Signs of manifest or suspected infections 3. Rheumatologic disease activity 4. Chronic renal failure (creatinine level >2.0mg/dL) 5. Recent (= 6 months) pulmonary embolism or venous thromboembolism 6. Does not sign the consent form 7. Contraindication for the use of glycoprotein IIb/IIIa inhibitors 8. Cardiac magnetic resonance (CMR) examination, for example, a person with a pacemaker or severe claustrophobia

Design outcomes

Primary

MeasureTime frame
Overall death in a 5-year follow-up

Secondary

MeasureTime frame
1. Levels of CK-MB isoenzyme and I-Troponin in association with presence of myocardial fibrosis 2. Left ventricle ejection disfunction assessed by CMR

Countries

Brazil

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 8, 2026