Patients with multivessel coronary artery disease and stable angina with formal indication for revascularization procedures Circulatory System Angina pectoris, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Stable angina 2. Multi-vessel coronary artery disease 3. Preserved left ventricular function 4. Formal indication to revascularization procedures (PCI or CABG)
Exclusion criteria
Exclusion criteria: 1. Recent myocardial infarction (=6 months) 2. Signs of manifest or suspected infections 3. Rheumatologic disease activity 4. Chronic renal failure (creatinine level >2.0mg/dL) 5. Recent (= 6 months) pulmonary embolism or venous thromboembolism 6. Does not sign the consent form 7. Contraindication for the use of glycoprotein IIb/IIIa inhibitors 8. Cardiac magnetic resonance (CMR) examination, for example, a person with a pacemaker or severe claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall death in a 5-year follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Levels of CK-MB isoenzyme and I-Troponin in association with presence of myocardial fibrosis 2. Left ventricle ejection disfunction assessed by CMR | — |
Countries
Brazil