Pre In vitro fertilisation (IVF) pipelle biopsy following a previous unsuccessful IVF cycle

A randomised controlled study of pre IVF pipelle biopsy of the endometrium in women with previous unsuccessful IVF treatment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN09447850

Enrollment

128

Registered

2012-06-07

Start date

2012-04-25

Completion date

Unknown

Last updated

2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subfertility Pregnancy and Childbirth Female infertility

Interventions

Intervention group: Local scratching of the endometrium (lining of the womb) of 64 patients in the cycle before the IVF treatment cycle. The biopsy is to be performed on Day 21 of the cycle preceding

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Between 23- 37 years of age 2. At least one previous unsuccessful IVF cycle 3. At least one good quality embryo transferred in the previous unsuccessful cycle

Exclusion criteria

Exclusion criteria: 1. Age less than 23 and more than 37 years 2. Previous poor quality embryos

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy rate	—

Secondary

Measure	Time frame
Implantation rate (number of embryos transferred divided by number of pregnancies)	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026