The RECOVER Study: Rehabilitation after Intensive Care

Conditions

Rehabilitation

Pam Ramsay, Guro Huby, Judith L. Merriweather, Lisa Salisbury, Janice Rattray et al. (7 authors)

BMJ Open2016-07-0137 citations

10.1136/bmjopen-2016-012041

Systemic inflammation after critical illness: relationship with physical recovery and exploration of potential mechanisms

David Griffith, Steff Lewis, Adriano G. Rossi, Jillian Rennie, Lisa Salisbury et al. (8 authors)

Thorax2016-04-2676 citations

10.1136/thoraxjnl-2015-208114

Increased Hospital-Based Physical Rehabilitation and Information Provision After Intensive Care Unit Discharge

Timothy Walsh, Lisa Salisbury, Judith L. Merriweather, Julia Boyd, David Griffith et al. (16 authors)

JAMA Internal Medicine2015-04-13279 citations

10.1001/jamainternmed.2015.0822

Exercise-based rehabilitation after hospital discharge for survivors of critical illness with intensive care unit–acquired weakness: A pilot feasibility trial

Bronwen Connolly, April Thompson, Abdel Douiri, John Moxham, Nicholas Hart

Journal of Critical Care2015-02-0778 citations

10.1016/j.jcrc.2015.02.002

A rehabilitation intervention to promote physical recovery following intensive care: a detailed description of construct development, rationale and content together with proposed taxonomy to capture processes in a randomised controlled trial.

Ramsay P, Salisbury LG, Merriweather JL, Huby G, Rattray JE, Hull AM, Brett SJ, Mackenzie SJ, Murray GD, Forbes JF, Walsh TS, RECOVER trial collaboration.

2014-01-2915 citations

10.1186/1745-6215-15-38

A randomised controlled trial evaluating a rehabilitation complex intervention for patients following intensive care discharge: the RECOVER study.

Walsh TS, Salisbury LG, Boyd J, Ramsay P, Merriweather J, Huby G, Forbes J, Rattray JZ, Griffith DM, Mackenzie SJ, Hull A, Lewis S, Murray GD.

2012-07-0219 citations

10.1136/bmjopen-2012-001475

Interventions

Participants will be randomised into one of two groups: Intervention group Standard ward-based care delivered by the NHS service with additional access to enhanced reh

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The patient has required 48 hours or more mechanical ventilation in the intensive care unit (ICU) 2. The consultant in charge of the patient considers them fit for discharge from the ICU

Exclusion criteria

Exclusion criteria: Current exclusion criteria as of 07/09/2012: 1. Primary neurological admission diagnosis (brain trauma; intracerebral bleed; stroke; Guillain-Barre syndrome) 2. The clinician in charge of care has agreed with the patient and/or family that only palliative care will be provided. 3. Patients currently receiving home ventilation or planning to commence a program of home ventilation 4. The patient is expected to be discharged from ICU to a non-study hospital where the intervention cannot be received 5. Gaining informed consent, following the intervention or follow-up is not feasible, despite resources available, due to communication difficulties 6. Patient currently enrolled in another RCT with similar endpoints 7. Patient aged <18 years at time of screening Previous exclusion criteria until 07/09/2012: 1. Primary neurological admission diagnosis (brain trauma; intracerebral bleed; stroke; Guillain-Barre syndrome) 2. Patients for whom a dedicated rehabilitation programme already exists (transplantation, stroke) 3. Patient currently enrolled in another RCT with similar endpoints

Design outcomes

Primary

Measure	Time frame
Rivermead Mobility Index, assessed at 3 months	—

Secondary

Measure	Time frame
The impact of the complex intervention on physical, psychological and social functioning will be measured at 3 months using: 1. Total, Physical Component Score, and Mental Component Score SF12v2 2. Euroqol EQ-5D score 3. Hospital Anxiety and Depression (HAD) questionnaire 4. Davidson's Trauma Scale score (DTS) 5. Nutritional Status (subjective global assessment of nutrition; SGA nutrition) 6. MRC Muscle Strength 7. Hand grip strength strength (HG dynamometry) 8. 2m timed up and go time 9. Visual analogue score 10. Health economic questionnaire 11. Process measures 12. Research Log of Generic Rehabilitation Assistants Assessments at 6 and 12 months - Rivermead Mobility Index, SF12v2, EQ-5D, HAD, DTS and health economic questionnaires, visual analogue score and overall patient satisfaction measure. Additional outcomes: 13. To compare patient and carer experiences between usual care and the new strategy 14. To evaluate the cost-effectiveness of the novel approach	—

Measure

Time frame

The impact of the complex intervention on physical, psychological and social functioning will be measured at 3 months using: 1. Total, Physical Component Score, and Mental Component Score SF12v2 2. Euroqol EQ-5D score 3. Hospital Anxiety and Depression (HAD) questionnaire 4. Davidson's Trauma Scale score (DTS) 5. Nutritional Status (subjective global assessment of nutrition; SGA nutrition) 6. MRC Muscle Strength 7. Hand grip strength strength (HG dynamometry) 8. 2m timed up and go time 9. Visual analogue score 10. Health economic questionnaire 11. Process measures 12. Research Log of Generic Rehabilitation Assistants Assessments at 6 and 12 months - Rivermead Mobility Index, SF12v2, EQ-5D, HAD, DTS and health economic questionnaires, visual analogue score and overall patient satisfaction measure. Additional outcomes: 13. To compare patient and carer experiences between usual care and the new strategy 14. To evaluate the cost-effectiveness of the novel approach

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Countries

United Kingdom

Outcome results

None listed