A prospective randomised trial of the use of tourniquet in total knee replacements

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN09327299

Enrollment

252

Registered

2007-09-28

Start date

2006-11-01

Completion date

Unknown

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Total knee replacement (TKR) Surgery Total knee replacement (TKR)

Interventions

Intervention: Tourniquet only inflated during cementation of the replacement. Control: Tourniquet inflated throughout procedure as in routine practice.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients undergoing total knee replacement at Stepping Hill Hospital under two named consultant surgeons

Exclusion criteria

Exclusion criteria: 1. History of peripheral vascular disease with absent popliteal or distal pulses 2. Calcification of artery on x-ray of knee 3. Previous vascular surgery on side of operation

Design outcomes

Primary

Measure	Time frame
Blood loss and change in haemoglobin level day 2 post-operatively	—

Secondary

Measure	Time frame
1. Range of movement six weeks post-op 2. Post-operative wound problems 3. Operative time 4. Blood transfusion 5. Complication rate	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026