How does dietary carbohydrate influence the formation of an atherogenic lipoprotein phenotype?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN09001687

Enrollment

Registered

2010-05-19

Start date

2009-04-01

Completion date

Unknown

Last updated

2022-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Diabetes Research Network, Primary Care Research Network for England

Interventions

The study will be a randomised, dietary intervention with a cross-over design. It will examine the effect of two test diets for 12 weeks, that differ in the quality of carbohydrate (high and low non-m

Eligibility

Inclusion criteria

Inclusion criteria: Not provided at time of registration

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Formation of high- and low-risk lipoprotein phenotypes	—

Secondary

Measure	Time frame
1. LDL kinetics, with a focus on the formation of small dense LDL 2. Sources of liver fat 3. Whether VLDL-TG is derived from increased DNL and/or systemically derived NEFA 4. VLDL kinetics, with focus on differential effects on the synthesis of VLDL-TG and VLDL-apoB	—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026