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Impact of iron/folate versus multi-micronutrient supplementation during pregnancy on birth weight: a randomised controlled trial in rural Western China

Impact of iron/folate versus multi-micronutrient supplementation during pregnancy on birth weight: a randomised controlled trial in rural Western China

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN08850194
Enrollment
7144
Registered
2006-12-14
Start date
2002-08-01
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low birth weight

Interventions

Hamlets were randomly assigned for women to receive one of the following three daily antenatal supplements: 1. Multi-micronutrients 2. Iron and folic acid 3. Folic acid alone (control) The multi-mic

Sponsors

United Nations Children's Fund (UNICEF) (China)
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women invited to participate in the trial must be less than 28 weeks of gestation

Exclusion criteria

Exclusion criteria: Women will be excluded from the trial if already taking iron, folate, and other micronutrients supplements for more than two weeks

Design outcomes

Primary

MeasureTime frame
1. Duration of pregnancy 2. Birth weight, length and head circumference 3. Haemoglobin level of pregnant women at the start of their third trimester

Secondary

MeasureTime frame
1. Compliance with supplements 2. Side effects of supplements 3. Complications of pregnancy: 3.1. Hypertension and preeclampsia 3.2. Antepartum haemorrhage 3.3. Infections 4. Type of delivery and type of assistance 5. Delivery complications: 5.1. Prolonged labour 5.2. Postpartum haemorrhage 5.3. Duration of maternal hospital admission 6. Early neonatal morbidity

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 4, 2026