Prophylaxis against Postoperative Vomiting (PaPoV) study: a prospective, controlled randomised double-blind trial comparing antiemetic prophylaxis with ondansetron, cyclizine and placebo (normal saline) in children undergoing plastic genito-urinary (GU) procedures

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN08630314

Enrollment

110

Registered

2003-09-12

Start date

1997-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Signs and Symptoms: Vomiting Surgery

Interventions

Prospective, controlled randomised double-blind trial.

Eligibility

Inclusion criteria

Inclusion criteria: Children undergoing elective plastic genito-urinary procedures between the ages of 3 and 5, American Society of Anesthesiologists (ASA) grade I & II. 55 Children in each group.

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Number of vomits in the first 24 h from the time of extubation; doses of anti-emetics given because of vomiting in the first 24 h; time to first oral intake; complications (obtained retrospectively from case notes).	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026