Prenatal iron supplementation versus iron supplementation plus deworming in reducing low birthweight in hookworm-endemic areas

Reducing low birthweight in hookworm-endemic areas: a randomised controlled trial (RCT) of prenatal iron versus iron plus mebendazole

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN08446014

Enrollment

1042

Registered

2005-09-09

Start date

2003-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaemia, hookworm infection Infections and Infestations Hookworm diseases

Interventions

One dose of mebendazole (500 mg) or placebo similar to the mebendazole. Daily iron supplements (60 mg iron) to both groups.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Second trimester pregnant women aged 18 to 44 years old 2. Not having received anthelmintic treatment for six months prior to randomisation 3. Consents to participate

Exclusion criteria

Exclusion criteria: 1. Women with severe anaemia (haemoglobin levels less than 80 g/I) 2. Women who have medical conditions for which follow-up is required

Design outcomes

Primary

Measure	Time frame
Mean infant birth weight	—

Secondary

Measure	Time frame
Change in maternal haemoglobin between baseline and delivery	—

Countries

Peru

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026