Diabetes Type 2 Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus
Conditions
Interventions
We will recruit 30 patients with type 2 diabetes in addition to 30 healthy controls in which we will characterise gut bacteria, measure intestinal permeability non-invasively and look for signs of inf
Sponsors
University of Surrey (UK)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Male 2. Aged 40-65 3. With or without Type 2 diabetes 4. Appropriate renal function
Exclusion criteria
Exclusion criteria: 1. Female 2. History of bowel disease 3. Abnormal renal function 4. Use of antibiotics in preceding 3 months 5. Regular use of NSAID medication 6. Use of diuretics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markers measured at baseline and after 12 weeks intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Gut bacteria measured at at baseline and after 12 week intervention 2. Insulin secretion measured at baseline and after 12 weeks intervention 3. Intestinal permeability measured at baseline and after 12 weeks intervention 4. Plasma endotoxin measured at baseline and after 12 weeks intervention | — |
Countries
United Kingdom
Outcome results
None listed