Esophageal Doppler guided fluid management Improves blood lactate clearance in multiple Trauma Patients: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN07606792

Enrollment

160

Registered

2006-10-19

Start date

2003-03-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple trauma patients Injury, Occupational Diseases, Poisoning Trauma

Interventions

Patients were randomised into protocol or control group according to the assigned admission number generated by admission office of hospital. Fluid management in control group patients was managed us

Eligibility

Inclusion criteria

Inclusion criteria: Ventilated patients with multiple trauma and estimated blood loss more than 2000 ml admitted to interdisciplinary Intensive Care Unit (ICU) of teaching university hospital in 2003 to 2005.

Exclusion criteria

Exclusion criteria: 1. Patients aged less than 18 years 2. Patients with traumatic brain injury requiring treatment of intracranial hypertension 3. Those with relative contraindications to the use of the esophageal Doppler probe, such as orofacial and esophageal injury or other known oropharyngeal and esophageal disease

Design outcomes

Primary

Measure	Time frame
1. Blood lactate clearance after 12 and 24 hours after ICU admission 2. Organ dysfunction development during ICU stay	—

Secondary

Measure	Time frame
1. Duration of ICU and hospital stay 2. The incidence of infectious complications during ICU stay	—

Countries

Czech Republic

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026