A study to investigate the Effect of Surgery and Compression on Healing And Recurrence in chronic venous ulceration

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN07549334

Enrollment

500

Registered

2007-04-13

Start date

1999-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic venous ulceration Circulatory System Venous ulceration

Interventions

Two groups were randomised to either compression therapy alone or compression plus superficial venous surgery.

Eligibility

Inclusion criteria

Inclusion criteria: Open or recently healed leg ulceration (within six months) of greater than four weeks duration between knee and malleoli, with Ankle Brachial Pressure Index (ABPI) above 0.85 and duplex evidence of superficial with or without deep venous reflux.

Exclusion criteria

Exclusion criteria: 1. Duplex imaging not possible 2. Patient unable/unwilling to give informed consent 3. Deep venous occlusion 4. Unfit for surgery (even under local anaesthetic) 5. Multilayer compression therapy not practical 6. Malignant ulceration

Design outcomes

Primary

Measure	Time frame
1. Ulcer healing 2. Ulcer recurrence	—

Secondary

Measure	Time frame
Ulcer free time	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 7, 2026