The effect of continuous positive airway pressure (CPAP) and non-invasive positive pressure ventilation (NIPPV) in acute cardiogenic pulmonary oedema (ACPO)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN07448447

Enrollment

1200

Registered

2003-04-25

Start date

2003-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular diseases: Heart disease Circulatory System Heart disease

Interventions

Continuous Positive Airway Pressure (CPAP) versus Non-Invasive Positive Pressure Ventilation (NIPPV) Please note that, as of 28 January 2008, the anticipated end date of this trial was updated from

Eligibility

Inclusion criteria

Inclusion criteria: 1. More than 16 years 2. Acute Cardiogenic Pulmonary Oedema (ACPO) principal clinical complaint 3. Confirmed diagnosis of ACPO

Exclusion criteria

Exclusion criteria: 1. Patients needing immediate life-saving interventions 2. Inability to provide informed consent

Design outcomes

Primary

Measure	Time frame
Added on the 12th June 2007: 1. NIV versus standard therapy: seven-day mortality 2. CPAP versus NIPPV: seven-day mortality or intubation	—

Secondary

Measure	Time frame
Added on the 12th June 2007: 1. Physiology 2. Side-effects including Myocardial Infacrtion (MI) 3. Cost-effectiveness	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 5, 2026