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Improving treatment selection for head and neck cancers and dysplasia

Improving treatment selection using PREDICtive and prognostic classifiers of Treatment Response for Head and Neck Cancers and dysplasia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN07132994
Enrollment
1400
Registered
2012-02-29
Start date
2012-05-01
Completion date
Unknown
Last updated
2016-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer Cancer Malignant neoplasm of head and neck

Interventions

The outcome data and samples of patients with oropharyngeal cancer receiving either chemoradiotherapy or surgery plus or minus chemo-radiotherapy are collated from each centre. Samples are then analys

Sponsors

University Hospitals Coventry & Warwick (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Oropharyngeal (tonsil or base of tongue) squamous carcinoma 2. Has a minimum 3 year follow up or to recurrence or death if occured before 3 years 3. Treatment by chemoradiotherapy or by surgery +/- post operative RT or chemoradiotherapy 4. Has clinical data including TNM staging available 5. Formalin fixed, paraffin embedded tissue block available 6. Male & female participants

Exclusion criteria

Exclusion criteria: 1. No follow-up data 2. Not of stated primary site

Design outcomes

Primary

MeasureTime frame
Survival measured at the end of the study

Secondary

MeasureTime frame
No secondary outcome measures

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026