Comparison of two physiotherapy rehabilitation programmes on the exercise capacity in patients with severe pulmonary hypertension

Comparison of two physiotherapy rehabilitation programmes on the exercise capacity in patients with severe pulmonary hypertension: a randomised study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN06900747

Enrollment

Registered

2010-07-15

Start date

2010-07-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary hypertension Circulatory System Other pulmonary heart diseases

Interventions

Intervention group 1: - endurance training: twice a week, 60 minutes, over 12 weeks Intervention group 2: - resistance training: twice a week, 60 minutes, over 12 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with pulmonary hypertension diagnosed by right heart catheterisation (mean pulmonary pressure [PAPm] > 25 mmHg) 2. New York Heart Association (NYHA) III - V 3. Walking distance (6-minutes walk test) > 150 meters 4. Patients with stable conditions on PH-related medication (single, double or triple therapy) 5. In stable condition for at least 3 months

Exclusion criteria

Exclusion criteria: 1. Skeletal or muscular restrictions which make the training impossible 2. New occurrence of syncope 3. Concomitant neurological diseases 4. Patients with neoplastic diseases 5. Mental disability making a proper evaluation of the study impossible 6. Age > 18 years < 85 7. Rapid fatal disease

Design outcomes

Primary

Measure	Time frame
Change in walking distance (6-minutes walk test) after 12 weeks of training and 12 weeks follow up	—

Secondary

Measure	Time frame
1. Change in VO2 submax (mobile spiroergometry) after 12 weeks of training and 12 weeks follow up 2. Change in scores for quality of life (SF-36 questionnaire) after 12 weeks of training and 12 weeks follow up 3. Change in scores (MRC-Dyspnoea scale) after 12 weeks of training and 12 weeks follow up 4. Change in daily activity measured with an accelerometer AiperMotion 320 after 12 weeks of training and 12 weeks follow up	—

Measure

Time frame

1. Change in VO2 submax (mobile spiroergometry) after 12 weeks of training and 12 weeks follow up 2. Change in scores for quality of life (SF-36 questionnaire) after 12 weeks of training and 12 weeks follow up 3. Change in scores (MRC-Dyspnoea scale) after 12 weeks of training and 12 weeks follow up 4. Change in daily activity measured with an accelerometer AiperMotion 320 after 12 weeks of training and 12 weeks follow up

—

Countries

Switzerland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026