A placebo controlled trial of medical treatment of submucous fibroids with gonadotropin releasing hormone (GnRH) analogues prior to hysteroscopic resection.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN06560767

Enrollment

Registered

2005-09-30

Start date

2003-02-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Gynaecological Surgery Other noninflammatory disorders of uterus, except cervix

Interventions

Women undergoing TCRM will be randomised to receive pre-operative treatment with gonadotropin releasing hormone (GnRH) or placebo. The duration of follow up was 6 weeks, post operatively

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Added 18/08/10: 1. Women found to have submucous fibroids on three-dimensional saline infusion sonohysterography (3D SIS) 2. Removal of fibroids by hysteroscopic transcervical resection of myoma (TCRM)

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

Measure	Time frame
Added 18/08/10: Completeness of fibroid resection	—

Secondary

Measure	Time frame
Added 18/08/10: 1. Duration of the TCRM 2. Fluid deficit recorded at TCRM 3. Resolution of symptoms post-operatively 4. Number of subsequent fibroid related operations	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026