Pilot study to test the usefulness of contractile reserve during dobutamine and exercise echo to predict recovery after mitral valve repair mitral valve prolapse

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN06298974

Enrollment

Registered

2007-09-28

Start date

2007-03-07

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular: Mitral valve disease Circulatory System Mitral valve disease

Interventions

Dobutamine vs standard practice

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients admitted to Eastbourne District General Hospital for mitral valve repair 2. Accepted for repair of mitral valve prolapse on clinical grounds and high probability of repairable valve

Exclusion criteria

Exclusion criteria: 1. Inability to perform test 2. Hypersensitivity to dobutamine or SonoView

Design outcomes

Secondary

Measure	Time frame
1. Baseline tissue Doppler contractile reserve 2. Baseline exercise test parameters 3. Neurohumoral markers 4. TOE and surgical parameters	—

Primary

Measure	Time frame
Death, myocardial infarction, hospitalisation for CHF.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026