Does targeted and quantified control of the microbiological environment within the ICU, using staff trained in microfibre cleaning and contamination bioload detection technology, reduce colonisation and healthcare-acquired infection?

Microfibre cleaning and contamination bioload detection technology versus standard cleaning in a critical care unit to reduce local contamination rates: a prospective randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN06298448

Enrollment

4000

Registered

2007-03-21

Start date

2007-04-02

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hospital-acquired infection Infections and Infestations Hospital-acquired infection

Interventions

A total environmental cleaning system based on microfibre and governed by standard operating procedures designed to achieve microbiological control of the entire near-patient environment. Follow-up s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients admitted to the critical care units of UCLH and Royal Free Hospitals. The critical care units are randomised to microfibre or standard cleaning. There is no patient intervention other than recording any infections developed.

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Proportion of the pooled results of all environmental swabs taken from bed areas on each day showing a target pathogen, e.g. MRSA	—

Secondary

Measure	Time frame
The rate of new acquisition by patients of MRSA and other target pathogens	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026