Treatment of hot flashes with low-dose risperidone

Treatment of hot flashes with low-dose risperidone: An uncontrolled pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN05964399

Enrollment

Registered

2010-07-08

Start date

2005-06-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hot flashes Urological and Genital Diseases Menopausal and other perimenopausal disorders

Interventions

Patients complete hot flash diaries regarding the frequency and severity of hot flashes everyday in a one-week baseline period, in the 3-month risperidone treatment period, and during the first two we

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Menopausal (perimenopausal or postmenopausal) women with at least a moderate severity (i.e., = 2 on a 0?4 scale) of hot flashes

Exclusion criteria

Exclusion criteria: 1. Menopausal women who take antipsychotic drug or/and antidepressants 2. Menopausal women who have breast cancer

Design outcomes

Primary

Measure	Time frame
The efficacy of risperidone for hot flashes is assessed by the average number of hot flashes per day, and the average daily hot-flash score (frequency × severity)	—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026