Cancer: Prostate Cancer Prostate cancer
Conditions
Interventions
Patients will have small gold seeds implanted into the prostate under local anaesthetic. Radiotherapy treatment planned as normal then randomised to be imaged by either:
1. Retrospective 'off-line'
Sponsors
Record Provided by the NHSTCT Register - 2007 Update - Department of Health (UK)
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Histological confirmed, previously untreated, locally confined adenocarcinoma of the prostate (T1-T3a, N0, M0) 2. PSA <50ng/ml prior to any hormone therapy 3. Suitable and fit for radical conformal therapy or intensity-modulated radiotherapy
Exclusion criteria
Exclusion criteria: 1. Other stages of prostate cancer than T1-T3a, N0, M0 as these may indicate different treatment 2. Patients not suitable for radiotherapy 3. Other malignancy within the previous 5 years (as they may have had treatment that will interfere with this study) 4. Indwelling urinary catheter 5. No total hip replacement (as this affects the imaging scanner).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean total displacement in tumour bed centre of gravity during a course of radiotherapy in both treatment arms | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mean daily displacement in tumour bed centre of gravity expressed as 3D co-ordinates 2. Intra- and inter-observer variability in marker localisation 3. Tolerance level of positional correction 4. Production of an on line image correction protocol | — |
Countries
United Kingdom
Outcome results
None listed