Development of a simple protocol to enhance compliance in home management of malaria

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN05620936

Enrollment

152

Registered

2007-10-30

Start date

2004-06-16

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Infections and Infestations Malaria

Interventions

Randomisation of the communities to the intervention and control groups was done by ballots. Interventions carried out at the intervention site: 1. Training of 'mother trainers' and community membe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Mothers with children 10 years or less who have febrile illness presumed to be malaria 2. Willingness of mothers to allow their child remain in study for a period of 14 days 3. Mothers who consent to their child having finger prick to collect blood for blood smears

Exclusion criteria

Exclusion criteria: 1. Child with severe illness or requiring parenteral medication 2. Child with other diseases, co-morbid with febrile illness Withdrawal Criteria: 1. Parents of children choosing not to continue with the study 2. Progression of illness in child

Design outcomes

Primary

Measure	Time frame
The mothers/caregivers were asked about the treatment given to the child during visits by the research assistants. The mothers/caregivers were asked to record these details in their diary, which was checked on Day 7 from recruitment at the time of collecting Day 7 blood sample for microscopy examination. These data were used to assess the following: 1. Correct use of chloroquine, measured in terms of dose, frequency and duration 2. Timeliness of commencing treatment (commencing treatment within 24 hours of noticing fever in child) 3. Treatment outcome, measured by mean parasite clearance time, fever clearance time, and progression of illness as reported by mothers/caregivers 4. Use of the protocol. Proportion of mothers who referred to the treatment protocol in the treatment of last episode of malaria in children	—

Measure

Time frame

The mothers/caregivers were asked about the treatment given to the child during visits by the research assistants. The mothers/caregivers were asked to record these details in their diary, which was checked on Day 7 from recruitment at the time of collecting Day 7 blood sample for microscopy examination. These data were used to assess the following: 1. Correct use of chloroquine, measured in terms of dose, frequency and duration 2. Timeliness of commencing treatment (commencing treatment within 24 hours of noticing fever in child) 3. Treatment outcome, measured by mean parasite clearance time, fever clearance time, and progression of illness as reported by mothers/caregivers 4. Use of the protocol. Proportion of mothers who referred to the treatment protocol in the treatment of last episode of malaria in children

—

Secondary

Measure	Time frame
1. Attack rate of malaria over a period of one year 2. Sensitivity and specificity of presumptive diagnosis of malaria by mothers/caregivers	—

Countries

Nigeria

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026