Multiple sclerosis Nervous System Diseases Multiple sclerosis
Conditions
Interventions
Patients who fulfil the inclusion criteria and have signed the consent form will be randomised to either the intervention group, which includes early rehabilitation (after less than 2 months from refe
Sponsors
The Danish Sclerosis Hospitals (Denmark)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Study participants will be recruited among all patients who are referred to the 4-week individual rehabilitation program during March 2012 to June 2013. Patients who are referred for a shorter rehabilitation program or theme courses are not eligible for the study. Participants must meet the following inclusion criteria: 1. Aged between 18 and 65 years 2. Diagnosis of multiple sclerosis (MS): relapsing remitting, primary or secondary progressive MS 3. Expanded Disability Status Scale (EDSS) score = 7.5 4. Can use a PC or have support/relative who can 5. Ability to read and understand sufficient Danish to understand instructions both orally and in writing, and having completed a consent form
Exclusion criteria
Exclusion criteria: 1. MS disease duration less than 6 months (the period from diagnosis to referral) 2. Experienced relapse within 3 months before the neurological appraisal 3. Recipient of sclerosis-specific hospital-based rehabilitation within the last 6 months 4. Cognition score, Kurtzke's Functional Systems (KFS) > 2 or cognitive limitations which hinder completion of self-reported questionnaires and/or giving informed consent 5. Moderate to severe depression; severe heart or lung disease 6. Drug or alcohol abuse 7. Any other illness that can impede participation in the study If participants develop a disease that might impair their participation in the study they will be excluded from the study at that time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Multiple Sclerosis Impact Scale version 2 (MSIS-29) and Functional Assessment of Multiple Sclerosis (FAMS) measured at baseline, at the start of the intervention, at intervention completion, 1, 6 and 12 months after baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mastery: Health Education Impact Questionnaire (heiQ) 2. Generic Quality of Life: EQ-5D and 15D 3. Expanded Disability Status Scale score (EDSS) 4. Resource consumption and costs for hospitals sclerosis for patients and their relatives, and for the rest of the healthcare service Measured at baseline, at the start of the intervention, at intervention completion, 1, 6 and 12 months after baseline. | — |
Countries
Denmark
Outcome results
None listed