Evaluating alternative approaches to packaging evidence and exploring the influence of context in guideline development in Kenya

Evaluating approaches to packaging evidence and exploring the influence of context in the process of developing evidence-informed guidelines for newborn care in rural hospitals in Kenya

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN05154264

Enrollment

Registered

2011-03-16

Start date

2010-05-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child health: evidence-informed guidelines Not Applicable

Interventions

Study 1. Randomised controlled trial Participants will be randomly allocated to receive the following ?graded-entry? evidence summary formats. A = Technical reviews + Systematic reviews (TR+SR) B =

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Participants will consist of a purposive sample of technical experts, practitioners and policy makers gathered to develop consensus guidelines during a planned 1 week neonatal stakeholder workshop.

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Study 1. Randomised controlled trial We will measure the impact of graded-entry evidence packs on participants? understanding of key messages resulting from the evidence (tracer topic) summaries e.g. issues around persistent dilemmas on the timing (?early? or ?delayed?) and rate of advancement (?rapid? or ?slow?) of feeding volumes in prematurely born sick infants. Study 2. Descriptive case study Data collection will focus on documenting processes involved in knowledge exchange and in the application of GRADE grid in guideline development. Emerging themes following the application of GRADE grid will be presented to all the participants for further discussions to promote consensus on draft essential newborn care (ENC) recommendations.	—

Measure

Time frame

Study 1. Randomised controlled trial We will measure the impact of graded-entry evidence packs on participants? understanding of key messages resulting from the evidence (tracer topic) summaries e.g. issues around persistent dilemmas on the timing (?early? or ?delayed?) and rate of advancement (?rapid? or ?slow?) of feeding volumes in prematurely born sick infants. Study 2. Descriptive case study Data collection will focus on documenting processes involved in knowledge exchange and in the application of GRADE grid in guideline development. Emerging themes following the application of GRADE grid will be presented to all the participants for further discussions to promote consensus on draft essential newborn care (ENC) recommendations.

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Secondary

Measure	Time frame
We will measure the impact of graded-entry evidence packs on participants? rating of their experience / satisfaction with the use of provided evidence packs. Rating will be done using a 5-point Likert scale tool (used successfully in previous studies measuring 3 domains of their experience: usability (ease of use as indicated by average time spent looking for information), practical value (e.g. in tailoring research evidence) and barriers to use of evidence pack (accessibility).	—

Measure

Time frame

We will measure the impact of graded-entry evidence packs on participants? rating of their experience / satisfaction with the use of provided evidence packs. Rating will be done using a 5-point Likert scale tool (used successfully in previous studies measuring 3 domains of their experience: usability (ease of use as indicated by average time spent looking for information), practical value (e.g. in tailoring research evidence) and barriers to use of evidence pack (accessibility).

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Countries

Kenya

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 24, 2026