Dental caries Oral Health Dental caries, unspecified
Conditions
Interventions
Prepared enamel lesions are placed in situ. Fluoridated toothpaste and fluoridated toothpaste plus GC ToothMousse™ will be given in a random order.
Visit 1: pre-trial wash-out (4 weeks)
Routine ortho
Sponsors
University of Liverpool (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The subjects are required: 1. To be between the ages of 12 to 17 years 2. To have adequate space between their last premolar and 1st standing molar to allow placement of the carrier on the archwire 3. To be in a suitable rigid archwire to allow placement of carrier 4. To be in good general health and oral health
Exclusion criteria
Exclusion criteria: The subjects will be excluded if: 1. They are allergic to milk products 2. They are taking or have taken antibiotics in the last 2 months 3. Unable to maintain adequate oral hygiene
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using Transvere MicroRadiography the mineral content of the enamel specimen will be carried out at baseline (before the trial begins) and then 4 weeks after being placed in the mouth. The following parameters will be analysed: 1. Mineral loss ?Z (vol%µm) 2. Lesion depth Ld (µm) and 3. Lesion width Lw (µm) | — |
Secondary
| Measure | Time frame |
|---|---|
| After the trial has finished, using the previously collected data the percentage change in mineral loss, lesion depth and lesion width is calculated | — |
Countries
United Kingdom
Outcome results
None listed