Effect of stopping proton pump inhibitors (PPI) on the incidence of Clostridium difficile diarrhoea (CDD)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN04808359

Enrollment

400

Registered

2004-09-30

Start date

2004-03-11

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System: Diarrhoea Digestive System Diarrhoea

Interventions

Randomised controlled intervention study to determine whether restriction of PPI use to National Institute for Clinical Excellence (NICE) approved indications has an effect on subsequent incidence of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 400 patients aged 65 or over admitted to hospital via Medical Assessment Unit (MAU) who are taking PPIs.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Incidence of CDD	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026