Glaucoma
Conditions
Interventions
1. Visual acuity: using Snellen chart
2. Slit-lamp examination: including examination of the cornea for development of any signs of stromal oedema, gonioscopy using Zeiss or Goldmann gonioscopy lens
Sponsors
Guy's and St. Thomas' NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged greater than 21 years 2. Lens opacity deemed enough to be causing reduced vision 3. Diagnosis of primary open angle glaucoma (POAG) (Group 1) or no glaucoma (Group 2). POAG defined as glaucomatous optic neuropathy together with an intraocular pressure (IOP) greater than 21 mmHg on at least one occasion, visual field defects (using the 24-2 test pattern on a Humphrey Field Analyser) and a gonioscopic angle width of 3 or 4 and normal in appearance. 4. Patient's willingness to participate in the study and ability to give informed consent
Exclusion criteria
Exclusion criteria: 1. Previous intraocular surgery 2. Previous ocular trauma that can cause damage to the drainage angle (e.g. angle recession) 3. International normalised ratio (INR) greater than 3.0 on the day of surgery (for the patients on warfarin) 4. Anterior segment neovascularisation 5. Chronic use of systemic or topical steroid 6. Any other concurrent ocular disease e.g. uveitis, diabetic retinopathy, corneal diseae, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outflow facility is measured using electronic Shiotz tonography at 3, 6 and 12 months post cataract surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Anterior chamber depth is measured using IOL master at baseline 2. Intraocular pressure is measured using Goldmann applanation tonometer at baseline, 3, 6 and 12 months 3. Intra- or post-operative complications is measured using clinically intra-operatively and post operatively 4. Development of glaucoma is measured using clinically and Humphrey visual field at baseline and 12 months | — |
Countries
United Kingdom
Outcome results
None listed