Oral magnesium for relief in pregnancy-induced leg cramps

A randomized, double-blinded, placebo-controlled trial of oral magnesium for relief in pregnancy-induced leg cramps

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN03989660

Enrollment

Registered

2011-11-14

Start date

2010-06-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnant women with leg cramps Pregnancy and Childbirth Pregnant women with leg cramps

Interventions

Oral magnesium biglycinate chelate (300mg/day) versus placebo Total duration of interventions is 4 weeks. Study drugs either magnesium or placebo will be administered orally at a frequency of three t

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Pregnant women were those with 14-34 weeks of gestation 2. Having pregnancy-induced leg cramps at least twice a week 3. No other medical disease 4. No concurrent obstetrics complication 5. No other prescriptions for leg cramps 6. No history of magnesium allergy

Exclusion criteria

Exclusion criteria: 1. Pregnant women with multifetal gestation 2. Subsequently developed pregnancy-induced hypertension and preterm labor treated with tocolytic agent

Design outcomes

Primary

Measure	Time frame
50% reduction in frequency of leg cramps	—

Secondary

Measure	Time frame
1. 50% reduction of cramp intensity 2. Side effects	—

Countries

Thailand

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026