Adult Attention Deficit Hyperactivity Disorder (ADHD) Mental and Behavioural Disorders Other disorders of adult personality and behaviour
Conditions
Interventions
60 participants will be randomly allocated to either:
1. CBT plus treatment as usual
16 one-hour therapy sessions taking place over 30 weeks in addition to usual medical follow-up appointments - typic
Sponsors
South London and Maudsley NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 17/12/2012: 1. Men and women aged 18-65 with a diagnosis of adult ADHD according to NICE guidelines i.e. if there was evidence from both the participant and the informant (where available) that: 1.1. the participant met DSM-IV criteria for Adult ADHD both in childhood and adulthood 1.2. the participant experienced at least moderate psychological, social and/or educational or occupational impairment in multiple settings 1.3. symptoms occurred in two or more settings including social, familial, educational and/or occupational settings. 2. Participants will have received a diagnosis either from the Adult ADHD Service, Maudsley Hospital, London, UK or another specialist/secondary care service (in this case a copy of the diagnostic report will be required) 3. Participants will either already be attending follow-up clinics, including psychoeducation workshops, or will have been recently referred to the service for medication follow-up or psychological treatment 4. Currently score 6 or more on the inattentive or hyperactive/impulsive subscale of the Adult Barkley Current Behaviour Scale (self-rated) 5. Clinical severity of at least a moderate level (Clinical Global Impression score of 4 or above) Previous inclusion criteria until 17/12/2012: 1. Men and women aged 18 to 65 who have received a diagnosis of adult ADHD in the Adult ADHD Service at the Maudsley Hospital, London, UK 2. Currently score 6 or more on the inattentive or hyperactive/impulsive subscale of the Adult Barkley Current Behaviour Scale (self-rated) 3. Clinical severity of at least a moderate level (Clinical Global Impression score of 4 or above) 4. If on medication to be on a stabilised dose as defined by no more than 10% change in medication dose over a two-month period
Exclusion criteria
Exclusion criteria: 1. Clinically significant anxiety disorder 2. Current episode major depression, current suicidality or self-harm (score of moderate or high suicidality on the M.I.N.I.) 3. Acquired brain injury 4. Primary diagnosis of psychosis or bipolar disorder 5. Pervasive developmental disorder 6. Active substance misuse/dependence in last three months 7. Verbal IQ <80 8. Diagnosis of a personality disorder 9. Participant not willing to comply with the requirements of an RCT 10. If the assessor does not perceive ADHD to be the current primary problem
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Adult Barkley Current Behaviour Scale (Barkley 2006) An 18-item self-report measure assessing ADHD symptoms, rated on a 4-point Likert scale 2. Work and Social Adjustment Scale (Mundt et al 2002) A reliable and valid self-report measure of impaired functioning attributable to an identified problem, consisting of 5 items, each rated on an 8-point scale All outcomes will be assessed at baseline, 30 and 42 weeks. There is an assessment at the 30-week point also in case of attrition and for further analyses, but 30-week measures will not be used as the main outcomes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 03/01/2012 1. Clinical Outcomes in Routine Evaluation Outcome measure (CORE-OM), (Evans et al 2002) 2. Hospital Anxiety and Depression Scale (HADS) 3. ADHD Beliefs Questionnaire 4. ADHD Behaviours Questionnaire 5. Rosenberg Self-Esteem Scale (Rosenberg 1965) 6. Autism Spectrum Quotient (Baron-Cohen et al 2001) *? 7. Global Impression scales (improvement** and satisfaction**) (adapted from Guy 1976 and used previously in Deale et al 1997) 8. Frost Multidimensional Perfectionism Scale (Frost et al 1990), Doubts about actions, Concern over mistakes, Parental Criticism and Parental expectations subscales 9. Beliefs about Emotions Questionnaire (Rimes et al 2009) Rated by nominated informant: 10. Adult Barkley Current Behaviour Scale 11. Global Impression scales (severity and improvement**) (adapted from Guy 1976 and used previously in Deale et al 1997) Rated by independent evaluator: 12. Global Impression scales (severity and improvement**) (adapted from Guy 1976 and used previously in Deale et al 1997) 13. Global Assessment of Functioning (Axis V, DSM-IV-TR) ? this is routinely administered during clinic assessments. This will only be included in the questionnaire pack if, for some reason, it has not already been completed * baseline only ** 30 and 42 weeks only Previous secondary outcome measures 1. Clinical Outcomes in Routine Evaluation Outcome measure (CORE-OM), (Evans et al 2002) 2. Hospital Anxiety and Depression Scale (HADS) 3. ADHD Beliefs Questionnaire 4. ADHD Behaviours Questionnaire 5. Rosenberg Self-Esteem Scale (Rosenberg 1965) 6. Autism Spectrum Quotient (Baron-Cohen et al 2001) *? 7. Global Impression scales (improvement** and satisfaction**) (adapted from Guy 1976 and used previously in Deale et al 1997) 8. Frost Multidimensional Perfectionism Scale (Frost et al 1990), Doubts about actions, Concern over mistakes, Parental Criticism and Parental expectations subscales 9. Beliefs about | — |
Countries
United Kingdom
Outcome results
None listed