Chronic tinnitus Ear, Nose and Throat Chronic tinnitus
Conditions
Interventions
Experimental intervention: Low frequency rTMS over the left auditory cortex with priming stimulation: 6Hz (90% motor threshold, 960 stimuli) followed by low frequency rTMS (110% motor threshold, 1Hz,
Sponsors
Regensburg District Clinic (Bezirksklinikum Regensburg) (Germany)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Female and male in- and outpatients 2. Age 18-70 years 3. Diagnosis of subjective chronic tinnitus 4. Duration of tinnitus more than 6 months
Exclusion criteria
Exclusion criteria: 1. Patients with conductive hearing loss of more than 15dB 2. Objective tinnitus 3. Treatable otologic disorder 4. Involvement in other treatments for tinnitus at the same time 5. Clinically relevant psychiatric comorbidity 6. Clinically relevant unstable internal or neurological comorbidity 7. History of or evidence of significant brain malformation or neoplasm, head injury 8. Cerebral vascular events 9. Neurodegenerative disorder affecting the brain or prior brain surgery; 10. Factors militating against the use of TMS (e.g. cardiac pace makers or other metal implants) 11. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in tinnitus severity according to the Tinnitus Questionnaire of Goebel and Hiller (baseline vs day 12). | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction of tinnitus severity as measured by the Tinnitus Questionnaire of Goebel and Hiller (TQ; THI) during the follow-up period (screening versus baseline versus days 18, 59, 90). | — |
Countries
Germany
Outcome results
None listed