Study of colonoscopic surveillance intervals after removal of colorectal adenomas

Randomised trial of colonoscopic surveillance intervals after removal of colorectal adenomas

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN02411483

Enrollment

785

Registered

2011-06-08

Start date

1979-01-01

Completion date

Unknown

Last updated

2017-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer Cancer Malignant neoplasm of colon

Interventions

Study of colonoscopic surveillance regimens. Allocation to regimen was by minimisation method. Patients were stratified into high and low risk groups by their characteristics at entry (age, malignancy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients attending St Mark?s Hospital between 1979-1990, with endoscopically removed adenomas or malignant lesions 2. 468 males and 317 females in the study, aged between 20 and 71

Exclusion criteria

Exclusion criteria: 1. History of inflammatory bowel disease 2. Surgical resection for CRC 3. A rectal villous adenoma 4. Patients older than 70 years

Design outcomes

Primary

Measure	Time frame
The primary outcome was the diagnosis of advanced neoplasia (advanced adenomas or colorectal cancer) during follow-up. An advanced adenoma was defined as an adenoma = 10 mm or with high grade dysplasia.	—

Secondary

Measure	Time frame
Detection of any adenoma during follow-up.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026