A magnetic resonance and histological investigation of articular cartilage damage in early stage degenerative disease of the hip joint and evaluation of synthetic labro-chondral graft implantation

A magnetic resonance and histological investigation of articular cartilage damage in early stage degenerative disease of the hip joint and evaluation of synthetic labro-chondral graft implantation (INTCLAPH)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN01688855

Enrollment

Registered

2013-08-22

Start date

2013-08-15

Completion date

Unknown

Last updated

2020-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Topic: Musculoskeletal

Interventions

tbc, tbc

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. History of hip pain. 2. Tönnis grade 0 or 1 radiographic changes. 3. Hip Joint Space Width (JSW) > 2 mm. 4. Arthroscopic confirmation of: 4.1. Labro-chondral split 4.2. Chondral defect grade 3 and 4 (Outerbridge, ICRS & UCL Classifications) 4.3. Chondral defect size range 0.5 ? 4.0 cm2. 5. Ability to provide informed written consent. Target Gender: Male & Female; Upper Age Limit 55 years ; Lower Age Limit 18 years

Exclusion criteria

Exclusion criteria: 1. OA Grade > 1 (Tönnis scale) 2. Inflammatory joint disease 3. Previous dislocation or fracture of the affected hip 4. Previous non-arthroscopic surgery to the affected hip 5. History of back pain 6. Age 55 years 7. BMI > 30 8. Hip joint space = 2 mm 9. Previous hip joint sepsis or osteomyelitis 10. Metabolic bone disease 11. Osteoporosis 12. Avascular necrosis 13. Associated neurological disease 14. Diabetes 15. Pregnancy 16. Chronic use of narcotics or oral steroids 17. Heavy alcohol intake on a regular basis 18. Inability to give consent or cooperate with the study protocol 19. Non-English speaking patients 20. Patients who move outside United Kingdom

Design outcomes

Primary

Measure	Time frame
tbc; Timepoint(s): tbc	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026