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Platelet-rich plasma (PRP) for jumper?s knee

The value of platelet-rich plasma injections in the treatment of the jumper?s knee: a double blind randomized trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN01626109
Enrollment
90
Registered
2014-09-24
Start date
2009-03-06
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patellar tendinopathy (jumper's knee) Musculoskeletal Diseases

Interventions

PRP, autologous blood or saline injection Blood (54cc) will be extracted from the elbow vein in every patient, because this is necessary to obtain 6cc PRP. The liquid to be injected will be placed i

Sponsors

Biomet Europe B.V. (Netherlands)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Jumper?s knee patients aged 18-55 2. Pain at the inferior pole of the patella for more than 3 months 3. Tendinosis or thickening compared to the contralateral side of > 3mm, detected with ultrasonography or MRI 4. Already undergone eccentric training for 6 weeks following a standardized protocol

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Injection in the patellar tendon in the last 3 months, irrespective of the applied substance 3. Operation on the patellar tendon in the past 4. At examination indications for intra articular pathology or patellofemoral pain syndrome 5. Chronic NSAID use in the last 3 months

Design outcomes

Primary

MeasureTime frame
VISA-P ? a validated questionnaire for patellar tendinopathy which assesses pain and function of the knee (100 = maximal score, indicating a normal functional knee, 0 = minimal score). This will be assessed at baseline, 6, 12, 26 and 52 weeks after injection treatment.

Secondary

MeasureTime frame
1. Ultrasound abnormalities (tendinosis zone, thickness of tendon and degree of neovascularisation) at baseline and 12 weeks after injection 2. Pain, measured using Visual Analogue Scale (VAS) score (0 = no pain, 10 = unbearable pain) 3. Costs of the treatments 4. Return to sport (level and duration)

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026