Alcohol addiction Mental and Behavioural Disorders Mental and behavioural disorders due to use of alcohol
Conditions
Interventions
A 2x2 factorial design with the following four arms:
1. Attentional bias retraining+approach bias retraining
2. Attentional bias retraining+approach bias placebo
Sponsors
University of Padua
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years, both female and male 2. Primary diagnosis of alcohol addiction disorder (DSM-IV-TR diagnostic criteria) 3. Alcohol abstinence for at least two months
Exclusion criteria
Exclusion criteria: 1. Neuro-cognitive problems or visual or hand-motoric handicaps 2. Severe neurological disorders (e.g., Korsakoff syndrome) 3. Comorbity with psychotic disorders 4. Low fluency in Italian language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the participants' treatment status, as assessed by the presence of any lapse or relapse during the 3 months after the intervention and the treatment status (medication intake, other form of therapeutic interventions), and clinical outcome, as defined by the clinical evaluation of the participants' therapeutic progress (successful or not). It is expected that, for each of the two CBM paradigms, participants in the real intervention condition will show a lower percentage of lapse or relapse and positive modification of their treatment status than participants in the control condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| The change in the automatic alcohol cognitive biases is assessed at the pre- and post-intervention measurement sessions, using both the trained measures of attentional bias and approach bias, as well as different tasks to test the generalization effects: the Color Stroop Task (as a measure of inhibitory executive control ability) and the Brief Implicit Association Test (as a measure of approach associations with alcohol). The approach and attentional bias are eventually assessed during the follow-up measurement session using the same stimuli of the post-intervention session, to check for the duration of the training effects. Secondary outcome measures (assessed at each measurement point) also include: 1. Other substances abuse (CORE questionnaire) 2. Motivation to treatment (Motivation to Treatment questionnaire) 3. Alcohol-related problems (AUDIT) 4. Craving (Obsessive Compulsive Drinking Scale) 5. Anxiety (State Trait Anxiety Inventory - Y questionnaire) 6. Depression symptoms (Beck Depression Inventory-II) | — |
Countries
Italy
Outcome results
None listed