The efficacy of lifestyle changes based on the principles of yoga in the management of bronchial asthma

Effect of yoga on pulmonary function, mast cell activation and quality of life in bronchial asthma: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN00815962

Enrollment

Registered

2008-10-21

Start date

2002-04-19

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma Respiratory Asthma

Interventions

Group I (yoga group) was given an integrated course on lifestyle based on the principles of yoga for 2 weeks while continuing with the conventional treatment. At the end of the 2-week training, partic

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The potential subjects (adults of either sex) went through a step-wise screening procedure which consisted of satisfying the following criteria: 1. Clinical history of episodic airway obstruction 2. Forced expiratory volume of one second (FEV1), or peak expiratory flow rate (PEFR) less than 80 percent of predicted normal and more than 10% or at least 200 mL increase in FEV1 15 minutes after administration of two puffs of salbutamol 3. Presence of at least two clinical criteria of mild or moderate bronchial asthma for at least 6 months

Exclusion criteria

Exclusion criteria: 1. Any respiratory tract infection during the past 4 weeks 2. On systemic or oral corticosteroid therapy 3. Smokers (any one who had smoked during the last one year was considered a smoker) 4. Concomitant major illness such as coronary heart disease, renal disease or diabetes 5. Practiced yoga or any other similar discipline during 6 months preceding the study

Design outcomes

Primary

Measure	Time frame
1. Spirometric indices of pulmonary function 2. Eosinophilic cationic protein as a marker of the course of the disease 3. The degree of exercise-induced bronchoconstriction as percentage of fall in FEV1 with exercise challenge 4. Urinary concentration of the prostaglandin D2 metabolite, 11 beta-Prostaglandin F2a (11 beta-PGF2a), before and after the exercise challenge as a marker of mast cell activation Recorded at regular intervals at 0 weeks, 2 weeks, 4 weeks and 8 weeks.	—

Measure

Time frame

1. Spirometric indices of pulmonary function 2. Eosinophilic cationic protein as a marker of the course of the disease 3. The degree of exercise-induced bronchoconstriction as percentage of fall in FEV1 with exercise challenge 4. Urinary concentration of the prostaglandin D2 metabolite, 11 beta-Prostaglandin F2a (11 beta-PGF2a), before and after the exercise challenge as a marker of mast cell activation Recorded at regular intervals at 0 weeks, 2 weeks, 4 weeks and 8 weeks.

—

Secondary

Measure	Time frame
1. Asthma quality of life: quality of life was measured by using a self-administered Asthma Quality of Life Questionnaire (AQLQ) which is available in bilingual form, i.e. English and Hindi (local Indian language) 2. Frequency of rescue medication Recorded at regular intervals at 0 weeks, 2 weeks, 4 weeks and 8 weeks.	—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 2, 2026