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An intervention to reduce sexual risk after Post-Exposure Prophylaxis for HIV following Sexual Exposure (Project PEPSE)

Multicentre RCT and economic evaluation of a psychological intervention together with a leaflet to reduce risk behaviour amongst men who have sex with men (MSM) prescribed post-exposure prophylaxis for HIV following sexual exposure (PEPSE)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN00746242
Enrollment
250
Registered
2012-01-06
Start date
2012-01-03
Completion date
Unknown
Last updated
2019-06-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infectious diseases and microbiology Infections and Infestations Human immunodeficiency virus [HIV] disease

Interventions

RCT conducted in Brighton and London is proposed. Participants will be MSM who have been prescribed PEP after sexual exposure. Those randomised to receive the intervention will receiv

Sponsors

Brighton & Sussex University Hospitals NHS Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Men who have sex with men (MSM) 2. Minimum age =16 years 3. A prescription for PEP after sexual exposure 4. Attending a Genito-Urinary Medicine (GUM) clinic 5. Willing and able to give written, informed consent

Exclusion criteria

Exclusion criteria: The following groups of patients will be excluded: those that do not consider themselves to be MSM, patients under the age of 16 years, people who have received previous psychological support from a clinical psychologist in relation to their sexual risk taking; people with learning difficulties; people unable to read study materials; people with no means of communication acceptable to the patient; people who are seeking PEP after sexual assault.

Design outcomes

Primary

MeasureTime frame
The proportion of risky sexual practices measured at 3, 6 and 12 months after the end of treatment

Secondary

MeasureTime frame
No secondary outcome measures

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 26, 2026