Sickle cell and thalassaemia Haematological Disorders Sickle-cell disorders
Conditions
Interventions
Please note that the anticipated end date of this trial has been extended to 30 April 2008 as of 14 December 2007 (Anticipated end date provided at time of registration: 30 September 2007). Closed to
(i.e. partners of women are only offered screening if the pregnant woman is found to be a carrier)
Group 3: In community-based secondary care, when women are booked by midwives with sequential partner
Sponsors
Department of Health (UK)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Eligible pregnant women receiving antenatal care at participating general practices 2. Aged 18 and over 3. Wanting to continue with the pregnancy 4. Carrier status is not documented in primary care records
Exclusion criteria
Exclusion criteria: 1. Women who do not want to continue with the pregnancies 2. Women who are more than 18 weeks gestation when reporting their pregnancies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time in pregnancy of offer of carrier screening for sickle cell and thalassaemia 2. Time in pregnancy of testing for carrier status for sickle cell and thalassaemia | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Rates of informed choice about undergoing the screening test 2. Time in pregnancy when women know the carrier status of the baby?s father 3. Couples emotional responses to carrier testing after they have received their test result | — |
Countries
United Kingdom
Outcome results
None listed