Diabetes mellitus (DM), periodontitis (PD) Nutritional, Metabolic, Endocrine Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention group:
1. Oral hygiene instructions and general explanations about PD
2. Intensive periodontal therapy, consisting of:
2.1. Extraction of compromised teeth
2.2. Scaling and root plannin
Sponsors
University of Perugia (Università degli Studi di Perugia) (Italy)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 35 to 70 years, either sex 2. Type 1 and 2 diabetes at the department of Endocrinology of Perugia Hospital 3. Presenting with mild to moderate periodontitis (defined as at least six sites in the mouth exhibited probing depths equal or greater than 4 mm; in each patient, bone loss was confirmed by an radiographic assessment)
Exclusion criteria
Exclusion criteria: 1. Presenting with signs of acute infections 2. Uncontrolled diabetes complications 3. Infectious diseases such as hepatitis or human immunodeficiency virus (HIV) infection 4. Patients requiring antibiotic prophylaxis before dental procedures 5. Patients who received a course of systemic antibiotic or periodontal therapy within the preceding 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in HbA1c after 8 months of therapy between cases and controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in periodontal parameters after therapy between cases and controls, recorded at baseline, 4 and 8 months after periodontal therapy. | — |
Countries
Italy
Outcome results
None listed