Condition 1: Prediabetes. Condition 2: Abdominal obesity. prediabetes Obesity, unspecified
Conditions
Interventions
Intervention 1: Intervention group 1: Participants will consume the complete hydroalcoholic extract of Vaccinium Arctostaphylos Fruit , prepared at the Medicinal Plants Research Institute of ACECR, as
Sponsors
University of Guilan
Eligibility
Sex/Gender
Female
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age between 30 and 50 years Female gender Diagnosis of prediabetes based on standard criteria Presence of abdominal obesity based on waist circumference No regular exercise program during the past 3 months No use of antioxidant supplements or glucose metabolism affecting drugs Willingness to participate and provide informed consent
Exclusion criteria
Exclusion criteria: Diagnosis of diabetes or use of glucose-lowering medications Cardiovascular, renal, hepatic, or severe chronic diseases Use of antioxidant or similar herbal supplements during the past 3 months Regular exercise training during the past 3 months Smoking or alcohol consumption Allergy to the study supplement Unwillingness to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma GLP-1 levels. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Fasting glucose. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Fasting insulin. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;HOMA-IR. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be calculated based on fasting glucose and fasting insulin values. | — |
Secondary
| Measure | Time frame |
|---|---|
| Triglycerides. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Total cholesterol. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;CholesterolLow-density. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Lipoprotein cholesterol High-density. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Glycosylated hemoglobin. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: It will be measured using blood sampling and laboratory methods.;Waist circumference. Timepoint: Before the intervention and after 4 weeks of intervention. Method of measurement: Waist circumference will be measured using a non-elastic measuring tape according to standard protocols. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShirin Jamshidi
University of Guilan
Outcome results
None listed