Zinc Deficiency in children.
Conditions
Interventions
Intervention 1: Intervention group: Daily intake of flavored bread made with zinc-fortified wheat flour (and iron and folic acid), along with single-serving packaged milk for 3 months (5 days/weak). I
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
7 Years to 9 Years
Inclusion criteria
Inclusion criteria: A 7 or 8 year old child who is studying in the first and second grade of primary school. Completion of the consent form by the legal guardian and the child At least one of the parents must be literate Not receiving zinc supplements in the last three months and currently. Not taking medications that interfere with zinc absorption or long-term/short-term use of certain medications such as hormonal drugs (growth hormone) and not following special or restricted diets such as vegetarianism Not taking any nutritional supplements in the last three months and/or currently, especially zinc, iron, calcium supplements. The absence of any physical defect or disability that would prevent the child from being able to measure their weight and height. The absence of any disease (and/or condition) and illness in the child.
Exclusion criteria
Exclusion criteria: Unwillingness to continue cooperation in the project Failure to complete the study outcomes at the end of the project, such as biochemical factors The occurrence of any allergy or intolerance to the product in the child Absence from school for any reason that leads to not receiving the product for more than 14 days Any illness during the study that causes the child to receive antibiotics (with any spectrum, amount and type) and penicillin The occurrence of any special medical conditions during the study, such as complications from blood collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum zinc. Timepoint: before and at the end. Method of measurement: a lab kit to measure serum zinc. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma fatty acid levels to assess the activity of fatty acid elongase and desaturase enzymes. Timepoint: before & after. Method of measurement: Lab.;Urinary Zinc. Timepoint: before, after, one-month follow up. Method of measurement: Lab.;Height and Weight. Timepoint: before, mid and at the end. Method of measurement: Standard Method.;Other Biochemical Tests. Timepoint: Before & After. Method of measurement: Lab.;Appetite and academic progress status, eating behaviour and food record. Timepoint: before, after. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHanie Barghchi
Mashhad University of Medical Sciences
Outcome results
None listed