Assessment of wound healing, pain intensity, and patient quality of life after palatal graft harvesting.
Conditions
Interventions
Intervention 1: Intervention group: Patients in this group received GLUBRAN® 2 tissue adhesive on the palatal area after surgery. Intervention 2: Control group: Participants in this group received onl
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients between 18 and 60 years of age Systemically healthy (ASA I) Without consumption of cigarettes, electronic cigarettes, waterpipe, or other forms of tobacco Having a clinical need for free gingival graft surgery around a tooth or dental implant
Exclusion criteria
Exclusion criteria: Severe gag reflex Active periodontal diseases Tooth mobility Occlusal traumas Absence from follow-up sessions Systemic diseases that impair proper tissue healing or contraindicate periodontal surgery (e.g., diabetes, high-dose steroid use, pregnancy, radiotherapy, chemotherapy, coagulation disorders, or use of drugs that interfere with wound healing)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of patient pain intensity. Timepoint: Up to two weeks after surgery. Method of measurement: Pain intensity is measured using the VAS (Visual Analog Scale).;Presence of bleeding. Timepoint: Up to one weeks after surgery. Method of measurement: through a questionnaire.;Quality of life. Timepoint: One, two, three, and four weeks after surgery. Method of measurement: via the OHIP-14 questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Epithelialization of the wound area. Timepoint: One, two, three, and four weeks after surgery. Method of measurement: Via application of hydrogen peroxide (H2O2) to the wound and evaluation of the extent of bubbling.;Color match of the area. Timepoint: One, two, three, and four weeks after surgery. Method of measurement: Analyzed using Adobe Photoshop CC 2017 software, the color difference between the healed area and the surrounding healthy tissue will be measured using standard colorimetric parameters, including brightness.;Residual wound area. Timepoint: One, two, three, and four weeks after surgery. Method of measurement: Standardized images will be taken of the wound site in the palatal area using a Canon EOS 800D camera. The wound surface area will be calculated and recorded in square millimeters using ImageJ software (NIH, Bethesda, USA). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhan Gholamian baee
Tehran University of Medical Sciences
Outcome results
None listed