Palatal wound after free gingival graft harvest. Encounter for surgical aftercare following surgery on the teeth or oral cavity
Conditions
Interventions
Intervention 1: Intervention group: After the surgery, one millilitr of Metformin hydrogel with neutral PH ( Carbapol, Hydroxypropyl Methylcellulose, Methylparaben, Propylparaben, Metformin 50mg/ml) a
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: All patients aged 18 to 70 years who require free gingival graft treatment around teeth or implants Systemically healthy Non-smokers( cigarettes, e-cigarettes, hookah or other forms of tobacco)
Exclusion criteria
Exclusion criteria: Active gag reflex Presence of periodontal disease, lack of sensation, tooth mobility and occlusal trauma Absence of maxillary canine to first molar teeth Excessive forces including mechanical forces from orthodontics and traumatic occlusion Systemic diseases that are contraindications for periodontal surgeries or interfere with tissue healing like diabetes, treatment with high-dose steroids, radiotherapy or immunosuppressive therapies, pregnancy, lactation, digestive problems, coagulation disorders (including liver diseases and bleeding disorders), history of using medications that interfere with healing or cause gingival enlargement Patients who do not attend follow-up sessions after surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Residual wound area. Timepoint: 0,7,14,21,28 days. Method of measurement: photography and measurement with Image J software.;Evaluation of epithelialization. Timepoint: 7,14,21,28 days after surgery. Method of measurement: oxygen bubbles observed after application of Hydrogen peroxide to the graft donor area (bubbling indicates incomplete wound healing).;Evaluation of tissue healing. Timepoint: 7,14,21,28 days. Method of measurement: Laundry`s healing index( palpation and direct examination by a specialist).;Color match. Timepoint: 7,14,21,28 days. Method of measurement: photography of wound and comparing images with Photoshop software. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Assessment. Timepoint: 1,7 days. Method of measurement: Visual Analogue Scale.;Bleeding Assessment. Timepoint: 1?7 days. Method of measurement: Questionnaire(presence or absence of bleeding).;Effect on Quality of life. Timepoint: 7,14,21,28 days. Method of measurement: Oral Health Impact Profile-14 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElaheh Shahraki
Tehran University of Medical Sciences
Outcome results
None listed