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Efficacy of Ondansetron on the Bronchoscopy / Efficacy of Lidocaine on the Bronchoscopy

A Comparative, Randomized, Double-Blind Study on the Efficacy of Ondansetron Versus Lidocaine on the Process of Diagnostic Bronchoscopy in Patients at Hazart-e Rasoul Akram Hospital, 1404

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20260503069252N1
Enrollment
100
Registered
2026-05-06
Start date
2026-06-05
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effectiveness of ondansetron and lidocaine on bronchoscopy.

Interventions

Intervention group: Group I – Ondansetron.

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with the need for diagnostic bronchoscopy who have been referred electively. Having written informed consent to participate in the study Having a specific age range (18 to 65 years old) Having a physical condition classified as ASA Class I or II.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The patient's willingness to undergo bronchoscopy again in the future. Timepoint: Immediately after the bronchoscopy procedure is completed and the patient recovers. Method of measurement: Using a Visual Analog Scale (VAS), usually in the range of 0 to 100 mm, 0 = absolute no desire, 100 = absolute desire.

Secondary

MeasureTime frame
Pain levels/vital signs/nausea and vomiting/coughing/patient cooperation/length of bronchoscopy. Timepoint: - Pain levels: measured with VAS before and after bronchoscopy.- Vital signs: including heart rate, blood pressure, and oxygen saturation (SpO2) at specified time intervals (before, during, and after the procedure).- Nausea and vomiting: measured with validated rating scales (scoring scale from 0 to 4).- Coughing: measured with validated rating scales or counting cough episodes during the procedure.- Patient cooperation and interaction: measured by a blinded evaluator using a standardized rating scale.- Bronchoscopy duration: time from bronchoscope insertion to bronchoscope exit. Method of measurement: - Pain levels: measured with VAS before and after bronchoscopy.- Vital signs: including heart rate, blood pressure, and oxygen saturation (SpO2) at specified time intervals (before, during, and after the procedure).- Nausea and vomiting: measured with validated rating scales (scoring scale from 0 to 4).- Coughing: measured with validated rating scales or counting cough episodes during the procedure.- Patient cooperation and interaction: measured by a blinded evaluator using a standardized rating scale.- Bronchoscopy duration: time from bronchoscope insertion to bronchoscope exit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mohammad Alaei Verki

Iran University of Medical Sciences

mohammadalaei9@gmail.com+98 21 6435 2455

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026