Comparison of blood supply of reverse sural flap with and without nerve preservation

Comparison of Viability and Perfusion of Reverse Sural Flap With and Without Sural Nerve

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260502069231N1

Enrollment

Registered

2026-05-09

Start date

2026-05-22

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft tissue defects in the foot and ankle area due to trauma, burns, or tissue necrosis. Major osseous defect, ankle and foot

Interventions

Intervention 1: Intervention group: The sural nerve, which is located deep in the deep fascia, is preserved during microscopic exploration, and the flap with pedicle can be rotated up to 180 degrees t

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Soft tissue defects in the foot and ankle area due to trauma, burns, or tissue necrosis Need for reconstruction with regional flap Written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Secondary trauma to the leg diabetes Limb ischemia Severe destruction of the distal lateral third of the lower leg Active infection at the surgical site Severe lateral malleolus crush

Design outcomes

Primary

Measure	Time frame
Flap function. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical assessment.;Flap color. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Doppler ultrasound and clinical evaluation.;Paresthesia. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical evaluation.;Infection. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical evaluation.	—

Measure

Time frame

Flap function. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical assessment.;Flap color. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Doppler ultrasound and clinical evaluation.;Paresthesia. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical evaluation.;Infection. Timepoint: In the first 24 hours (every two hours), the first 48 hours (every 8 hours), and after discharge on the third day, weekly for up to a month, and then quarterly and six-monthly reviews. Method of measurement: Clinical evaluation.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahab Ghassemi

Iran University of Medical Sciences

shahab_ghassemi@yahoo.com+98 21 8870 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026