Evaluation of the Combined Effect of Atorvastatin and Collagen Foam on Bone Healing After Tooth Extraction Using CBCT Images

Radiographic study of simultaneous use of atorvastatin and collagen foam in dentate gingival recession on CBCT images.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20260427069191N1

Enrollment

Registered

2026-05-05

Start date

2026-05-15

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The health condition studied is alveolar bone defect/healing after tooth extraction. Tooth extraction leads to physiological bone resorption and delayed bone regeneration in the extraction socket, which may affect future prosthetic or implant treatment outcomes.. Chronic periodontitis, localized

Interventions

Participants allocated to the intervention group will receive local alveolar ridge preservation treatment immediately after tooth extraction using a sterile absorbable collagen foam scaffold impregnat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults aged 18 years or older requiring extraction of at least two teeth and subsequent bone regeneration procedures in the extraction sites. Patients with stable periodontal status and good oral hygiene Ability and willingness to comply with study requirements, including attendance at scheduled follow-up visits for up to 3 months. Provision of written informed consent prior to participation.

Exclusion criteria

Exclusion criteria: Presence of active local or systemic infection/inflammation. Presence of systemic or local diseases that may interfere with bone healing, including but not limited to uncontrolled diabetes mellitus (HbA1c >7%), osteoporosis, and hyperparathyroidism. Current or previous use of medications known to interfere with bone healing Chronic corticosteroid therapy. Known allergy or hypersensitivity to bone graft materials, collagen foam, or atorvastatin.

Design outcomes

Primary

Measure	Time frame
Radiographic bone healing of the extraction socket will be assessed using CBCT imaging by measuring bone density and bone fill percentage at 3 months after the intervention. Timepoint: Three months after the intervention. Method of measurement: The outcome will be measured using cone-beam computed tomography (CBCT) images to assess bone density and bone fill percentage in the extraction socket.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Noravesh

Islamic Azad University

aidanazarzade95@gmail.com+98 910 916 8830

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026